Medi-Spa Medical Grade Skin Care niko_logo
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The Niko Medical Grade Skin Care Line is a series of professional anti-aging topical serums specifically designed for the medical industry and professional spas.

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Niko's mission is to offer the medical and spa industry skin care products with high, safe levels of medical grade anti-aging ingredients, while maintaining the utmost levels of natural elements. The resulting affects are visibly noticeable within minutes of application.

The Niko Skin Care line offers a truly remarkable experience with products containing concentrations of medical grade ingredients that act to counter the aging process. Generally resulting in the disappearance of fine lines and smooth out the deeper creases, almost instantaneously.

Niko cares for the environment; by using environment friendly packaging that can be recycled at any local recycling program, not only reduces the impact on the environment, but it allows the majority of the resources to be directed towards developing and producing the highest standard product possible. Niko products are not tested on animals.

Simplicity and effectiveness is key in Niko's Medical Skin Care line. Niko's anti-aging regime consists of day-time and night-time treatment and follows a simple rule;
Clear Contents ='First' to be applied to clean skin
Cream Contents="Second' to be applied to the skin over the clear.


To Summarize: Clear First, Cream After
icukit_trio

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ICU KIT
Eye Firming Gel & Eye Soothing Cream
This top selling eye kit combines the firming of the I.C.U Eye Firming Gel, with the calming, nourishing effects of the I.C.U Eye Soothing Cream. For best results we recommend you use your I.C.U Kit morning and night.

Directions: Apply 1-2 drops of the I.C.U Eye Firming Gel around the eye area. Follow with 1-2 drops of the I.C.U Eye Soothing Cream over the I.C.U Eye Firming Gel. Recommended for day use

Niko Rule: ICU KIT
daytime_medispa nighttime_medispa Apply First Apply After
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  chckmark_medispa Eye Firming Gel chckmark_medispa Eye Soothing Cream

Eye Firming Gel Ingredients:
Water
Aloe: Moisturizing, healing
Sodium Hyaloronate solution: Moisturizing, holds 1000 times its weight in moisture
Glycerine: Humectant, moisturizing
Grape Seed Extract: Antioxidant
Chamomile Extract: Soothing, healing
Green Tea Extract: Excellent antioxidant
Willowherb extract: Conditioning, helps eliminate dark circles
Yeast Extract (plant collagen): Moisturizing, revitalizing
Beta-Glucan: Anti-inflamatory, reduces wrinkles, healing
Polysorbate 20: Emulsifier
Phenozyethanol: Preservative
Carbomer: Emulsion stabilizer
Triethanoiamine: Emulsifier and ph adjuster
Quatemium-15: Preservative

Eye Soothing Cream Ingredients:
Water
Stearic Acid: Emulsifer, vegetable base
Tridecyl Stearate: Conditioning agent and emollient
Neopentyl Glycol Dicaprylate: emollient
Dicaprate (and) Tridecyl Trimellitate: Conditioning
Glyceryl Stearate: Humectant
Isopropyl Myristate: found in nutmeg, excellent moisturizer
Propylene Glycol: humectant, moisturizer
Hydrogenated Polysobutene: Conditioning
Cetyl acetate: Emulsifier
Acetylated lanolin Alcohol; Mositurizing emolliant
Squalane: excellent moisturizer
Triethanolamine: Emulsifier, ph adjuster
Cetyl alcohol: Emulsifier
Carbomer: Thickening agent
Diazolidinyl Urea: Antiseptic
Aloe Barbadensis Gel: Moisturizing, healing
Camellia Sinensis: Soothing
Propelyn Glycol; Moisturizing
Cucumber extract: Soothing, moisturizing, tightening.
Allantoin: Healling
Wheat germ oil: Antioxidant
Tocopherol: Antioxidant vitamin E
Sodiuim Hyaluronate: Moisturising, firming
Retinyl Palmitate; Vitamin A, conditioning
LiquidPure_MicroHyaluronic

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Liquid Pure
Micro-Hyaluronic Serum
Niko Liquid Pure is pure Micro-Hyaluronic acid solution designed specifically for the medical professionals. Niko Liquid Pure is natures' moisturizer, Hyaluronic acid, is naturally produced in our skin. During the skin's natural aging process, depleted levels of Hyaluronic acid, results in the outer layers of the skin becoming dry, wrinkled and less resilient. Niko Liquid Pure's low molecular composition readily moisturizes and hydrates the skin, smoothing out wrinkles and fine lines, with results you can see immediately. Hyaluronic acid is used by leading plastic surgeons to moisturize sensitive skin areas during surgery. It is also recommend by the medical profession to prolong the effects of cosmetic injectibles, with continued use. The Medical Profession acknowledges that Hyaluronic is one of the key ingredients to combat aging. Hyaluronic acid absorbs 1000 time its weight in moisture and it is often referred to the 'fountain of youth'.

Directions: For best results follow this simple day time regime: cleanse and tone using your favorite Niko products. After applying your Niko ICU kit, apply 1 to 2 pearl sized drops of Liquid Pure to the face and neck. Let dry and finish with Niko Medical Day Spa Moisturizer or the USDA Organic Kakadu Plum Antioxidant Day Moisturizer.
Rules to remember:
Clear Contents ='First' to be applied to clean skin
Cream Contents="Second' to be applied to the skin over the clear.

Niko Rule: Liquid Pure
daytime_medispa nighttime_medispa Apply First Apply After
chckmark_medispa
  chckmark_medispa Liquid Pure

     Medical Day Spa Moisturizer
chckmark_medispa                or
     Organic Kakadu Plum Antioxidant Day Cream

Ingredients: Purified water, vegetable glycerine, yeast extract (phyto hyaluronic acid), hydroxyethylcellulose, vitamin E acetate, phenoxyethanol (and) caprylyl glycol (and) sorbic acid

45MediDaySpayMoisturizer

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Medical Day Spa Moisturizer
Hyaluronic Base Day Moisturizer
Niko's Medical Day Spa Moisturizer is an anti-aging moisturizer designed specifically for the medical profession.
While most manufactures use a fraction of a percent of hyaluronic acid, Niko's Medical Day Spa Moisturizer boasts Hyaluronic acid as their base ingredient. Without the use of fillers, perfumes and colorants this effective formula is rich in emollients and anti-oxidants, leaving soft and supple, without feeling greasy of sticky.
Niko Medical Day Spa Moisturizer is recommended over Liquid Pure as a day-time anti-aging treatment. It seals in the Liquid Pure, prolonging absorption and provides further moisturizing protection for the skin all day long. The natural SPF 15 also protects the skin against the sun's rays. The Niko Medical Day Spa Moisturizer and Liquid Pure is also a great base for applying the Niko Make-up foundation over.
Directions: After applying Niko Liquid Pure to the entire face and neck as per directions, apply Niko Medical Day Spa Moisturizer to the entire face and neck and let dry.
Rules to remember:
Clear Contents ='First' to be applied to clean skin
Cream Contents="Second' to be applied to the skin over the clear.

Niko Rule: Medical Day Spa Moisturizer
daytime_medispa nighttime_medispa Apply First Apply After
chckmark_medispa
  chckmark_medispa (clear)

chckmark_medispaMedical Day Spa Moisturizer

Ingredients:
Water:
vehicle
Sodium Hyaluronate Cross linked:
wrinkle filler, holds moisture and maintains resilience
C12-15 Alkyl Benzoate:
an emollient ester that provides light conditioning
Panthenol (Pro Vitamin B5):
acts as a penetrating moisturizer
Ascorbic Acid (Vitamin C):
skin lightening, anti-wrinkle, and antioxidant properties
Tocopheryl Acetate (Vitamin E):
antioxidant, moisturizing conditioner
Tocopheryl Linoleate:
promotes soft, supple skin
Algae Extract:
Mineral-rich and helps retains skin moisture
Rosa Canina Fruit Oil:
also known as "Rosehip Oil", high in essential fatty acids, has a soothing & rejuvenating effect
Persea Gratissima (Avocado) Oil:
contains protein and amino acids that helps promote regeneration
Camellia Oleifera (Green Tea):
antibacterial, anti-inflammatory and antioxidant
Camellia Sinensis (White Tea):
antioxidant that helps restore skin's resiliency
Vitis Vinifera (Grape) Seed Extract:
hypoallergenic antioxidant
Centella Asiatica Extract:
helps stimulate production of collagen
Echinacea Angustifolia Extract:
also known as "Coneflower extract" contains essential fatty acids and hydrates
Sodium Ascorbyl Phosphate:
antioxidant that helps liberate Vitamin C in the skin
Isocetyl Stearate:
emollient, conditioner
Phenoxyethanol:
preservative
Palmitoyl Tripeptide-3:
helps stimulate production of collagen
Palmitoyl Oligopeptide:
cleansing agent and conditioner
Palmitoyl Oligopeptide 3:
helps to stimulate collagen production
PEG-100 Stearate:
emollient and emulsifier
Cyclopentasiloxane:
skin conditioning agent
Geranylgeranone:
helps to improve skin's elasticity
Glycosaminoglycans:
helps to improve skin's firmness
Glyceryl Stearate:
Emulsifier and helps to soften skin
Allantoin:
soothing skin protectant
Titanium Dioxide:
natural sun screen

SuperCSerum

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Super C Serum
15% L-Ascorbic Acid Serum with Mtrixyl™
Niko has taken L-Ascorbic Vitamin C to the next level. Niko's pharmaceutical grade 15% L-Ascorbic Acid has been designed for the medical profession. Super C L-Ascorbic Acid has been combined with Matrixyl™ at 4% giving the benefits of a 30% L-Ascorbic Acid, while stabilizing the Vitamin C.
Super C with Matrixyl™ stimulates the synthesis of collagen, increasing skin elasticity. Super C also evens out pigmentation, lightens and tightens the skin.

Directions: Use Nightly. After cleansing and toning with your favorite Niko products it's time to follow the Niko 'Two Step' procedure to doctor recommended anti-ageing treatment; Dispense a few drops of Super C on the palm of your hand, dab your finger on the serum and gently pat on sensitive areas, such as the underside of the eye and around the mouth area . Apply the remainder of the serum to the rest of the face and hands. Follow with Medical Day Spa Moisturizer or USDA Organic Kakadu Plum Antioxidant Night Cream.
Rules to remember:
Clear Contents ='First' to be applied to clean skin
Cream Contents="Second' to be applied to the skin over the clear.

Niko Rule: Super C
daytime_medispa nighttime_medispa Apply First Apply After

chckmark_medispa chckmark_medispa Super C

     Medical Day Spa Moisturizer
chckmark_medispa                or
     Organic Kakadu Plum Antioxidant Night Cream

Active Ingredients:
Sodium Ascorbyl Phosphate L-Ascorbic Acid 15%:
Produces collagen in skin
Propylene Glycol :
Moisturizer
Glycerin:
Moisturizer
Citric Acid:
PH control and stabilizer
Carbomer:
Makes Matrixyl
Palmitoyl Oligopeptide:
Makes Matrixyl™
Palmitoyl Tetrapeptide-7:
Makes Matrixyl™
Sodium Hyaluronate:
Holds 1000 times its own weight in moisture. Hydratates the skin
Panthenol:
Pro Vitamin B
Urea:
Moisturizer
Allantoin:
Moisturizer, skin healer
Carbomer:
Makes Matrixyl

Matrixyl™   Claim Substanciation

Matrixyl™: is the trademark name for one of the most effective peptide molecules used in the in skin rejuvenation known as palmitoyl pentapeptide-4 (Pal-KTTKS). It is a lipopeptide that combines a fatty acid with 5 linked amino acids. The fatty acid is used to increase the compound's skin absorption.

An independent study conducted by cosmetic scientists revealed that 3% MatrixylTM temporarily produced a significant reduction in moderate to deep wrinkles

  IN VITRO  
Summary of results obtained by Katayama (1993) on peptide (KTTS):
-Stimulation of collagen I & III and fibronectin synthesis      +320% with 50μM
Neosynthesis
-Stimulation of collagen IV synthesis of aged fibroblasts     +257% with 4% Matrixyl™
-Stimulation of glycosaminoglycan synthesis on fibroblasts +267% with 2% MatrixylTM ™
  EX VIVO  
The trial included five parameters:
Global area of wrinkles
Density of furrows
Volume of wrinkles
Mean depth of the main wrinkle
Roughness of skin.
Neosynthesis of collagen on human skin biopsies:
-Stimulation of collagen synthesis:
CollegenSynthesisGraph
  MATRIXYL 2% (2ppm pal-KTTKS) +30%
MATRIXYL 4% (4ppm pal-KTTKS) +117%
Vitamin C (1000ppm) +42%
 
    IN VIVO  

The outcome documented changes as dramatic as 68% for surface area occupied by deep wrinkles. The surface area occupied by moderate wrinkles was reduced by an average of 51%. The results were also said to improve the longer the study participants used the product indicating that the peptide's effect in the skin was progressive. What also caused great interest in the product was that every trial participant showed noticeable improvements within the first two weeks of use.

The trial indicated findings such as:
Overall collagen synthesis by up to 117%.
Hyaluronic acid synthesis by up to 267%.

Against placebo:
25 volunteers / Twice-dayly application on half face of a cream containing 3% Matrixyl™ versus placebo / Image analysis by profilometry
  -Wrinkle depth -21.6%
-Roughness -16.4%
-Wrinkle volume -24.4%
-Main lines density -46.8%
-Wrinkle surface -67.8%
 




"Matrixyl™ peptide belongs to the family of Matrikines (Peptidic fragments, messengers of the natural process of tissue repair), is designed as an efficient anti-wrinkle active ingredient. It acts through specific mechanisms, without any toxicological danger."


 

Excerpt from : http://hubpages.com/hub/Matrixyl

Excerpt from: http://thewinspacollection.com/matrixyl_blue.pdf
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